Introduction
Diets have shifted towards the consumption of processed food. The NOVA system classifies it into (1) minimally processed, (2) culinary ingredients, (3) processed foods (PF) and (4) ultra-processed foods (UPF). There is evidence that PF and UPF are related with disease outcomes (obesity, diabetes, cardiovascular disease, cancer), and mortality but the metabolic signatures...
Introduction
Worldwide, more than 1.9 million new colorectal cancer cases and 935,000 deaths were estimated to occur in 2020, representing about one in 10 cancer cases and deaths. Previous studies found evidence of a positive association between the NOVA 4 consumption and colorectal cancer but few studied the association between the four Nova groups and the different anatomical...
Introduction
Lipids are involved in many metabolic processes that may be relevant for cancer development. However, the role of specific lipid metabolites on colorectal cancer risk is unclear.
Methods
In a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC), we examined associations between pre-diagnostic circulating concentrations of 97...
Introduction
It has been postulated that adopting healthy behaviours such as limiting alcohol consumption, maintaining a healthy weight, engaging in regular physical activity, not smoking, and eating a healthy diet could reduce the risk of breast cancer. Within the EPIC cohort, we previously combined these five lifestyle factors, assessed at recruitment, into a single Healthy Lifestyle...
